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Expression of the Shh/Bmp4 signaling pathway during the development of anorectal malformations in a male rat model of prenatal exposure to di(n-butyl) phthalate
Author(s) -
Enhui Li,
Shengjie Liang,
Wen-Lan Sun,
Dongliang Xu,
Yan Hong,
Shujie Xia,
Juntao Jiang
Publication year - 2014
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c4tx00095a
Subject(s) - phthalate , prenatal development , fetus , medicine , signal transduction , biology , bioinformatics , microbiology and biotechnology , pregnancy , chemistry , genetics , organic chemistry
Sonic hedgehog (Shh)/bone morphogenetic protein 4 (Bmp4) is an androgen-regulated signaling pathway that has been shown to be crucial for embryonic development.

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