Continuous flow chemistry: a discovery tool for new chemical reactivity patterns | Zendy

Jan Hartwig | Zendy; Jan B. Metternich | Zendy; Nikzad Nikbin | Zendy; Andreas Kirschning | Zendy; Steven V. Ley | Zendy

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Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

Author(s) -

Jan Hartwig,

Jan B. Metternich,

Nikzad Nikbin,

Andreas Kirschning,

Steven V. Ley

Publication year - 2014

Publication title -

organic and biomolecular chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.923

H-Index - 146

eISSN - 1477-0539

pISSN - 1477-0520

DOI - 10.1039/c4ob00662c

Subject(s) - continuous flow , reactivity (psychology) , chemistry , flow chemistry , nanotechnology , computer science , biochemical engineering , materials science , engineering , medicine , alternative medicine , pathology

Continuous flow chemistry as a process intensification tool is well known. However, its ability to enable chemists to perform reactions which are not possible in batch is less well studied or understood. Here we present an example, where a new reactivity pattern and extended reaction scope has been achieved by transferring a reaction from batch mode to flow. This new reactivity can be explained by suppressing back mixing and precise control of temperature in a flow reactor set up.

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