Antimicrobial effects of copper(ii ) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action
Author(s) -
Karrera Y. Djoko,
Brett M. Paterson,
Paul S. Donnelly,
Alastair G. McEwan
Publication year - 2014
Publication title -
metallomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 75
eISSN - 1756-591X
pISSN - 1756-5901
DOI - 10.1039/c3mt00348e
Subject(s) - antimicrobial , copper , mode of action , chemistry , semicarbazone , combinatorial chemistry , biochemistry , stereochemistry , organic chemistry
The copper( ii ) complexes of bis-thiosemicarbazones such as Cu(atsm) and Cu(gtsm) display potent antimicrobial properties via inhibition of respiratory dehydrogenases.
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