Human oral cancer cells with increasing tumorigenic abilities exhibit higher effective membrane capacitance
Author(s) -
Kristina Xiao Liang,
Karen A. Graham,
A. C. Johannessen,
Daniela Elena Costea,
Fatima H. Labeed
Publication year - 2014
Publication title -
integrative biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 70
eISSN - 1757-9708
pISSN - 1757-9694
DOI - 10.1039/c3ib40255j
Subject(s) - cancer , cancer cell , membrane , capacitance , microbiology and biotechnology , membrane potential , cancer research , chemistry , biophysics , biology , biochemistry , medicine , electrode
Although cells with tumorigenic/stem cell-like properties have been identified in many cancers, including oral squamous cell carcinoma (OSCC), their isolation and characterisation is still at early stages. The aim of this study is to characterise the electrophysiological properties of OSCC cells with different tumorigenic properties in order to establish if a correlation exists between tumorigenicity and cellular electrical characteristics.
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