A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding
Author(s) -
John B. Mangrum,
Brigitte J. Engelmann,
Erica J. Peterson,
John Ryan,
Susan J. BernersPrice,
Nicholas P. Farrell
Publication year - 2014
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/c3cc49695c
Subject(s) - glycan , bioinorganic chemistry , biomolecule , oligosaccharide , chemistry , rna , biochemistry , dna , function (biology) , enzyme , computational biology , nanotechnology , glycoprotein , biology , microbiology and biotechnology , materials science , gene
Metalloglycomics - the effects of defined coordination compounds on oligosaccharides and their structure and function - opens new areas for bioinorganic chemistry and expands its systematic study to the third major class of biomolecules after DNA/RNA and proteins.
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