Novel drug carriers: from grafted polymers to cross-linked vesicles
Author(s) -
Jiangtao Xu,
Qiang Fu,
Jing Ren,
Gary Bryant,
Greg G. Qiao
Publication year - 2012
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/c2cc37319j
Subject(s) - conjugate , vesicle , polymer , copolymer , drug , anticancer drug , drug carrier , chemistry , drug delivery , combinatorial chemistry , nanotechnology , materials science , chemical engineering , polymer chemistry , organic chemistry , biochemistry , membrane , pharmacology , medicine , mathematical analysis , mathematics , engineering
A simple and straightforward method of self-assembling grafted copolymers was developed to fabricate cross-linked polymer vesicles, which could conjugate anticancer drug cis-platinum and possess the capability of a high drug loading content, and a steady release rate.
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