Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery | Zendy

Hong-Yuan Lian | Zendy; Ming Hu | Zendy; Chia-Hung Liu | Zendy; Yusuke Yamauchi | Zendy; Kevin C.W. Wu | Zendy

Open Access

Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Author(s) -

Hong-Yuan Lian,

Ming Hu,

Chia-Hung Liu,

Yusuke Yamauchi,

Kevin C.W. Wu

Publication year - 2012

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/c2cc31708g

Subject(s) - biocompatible material , cisplatin , drug delivery , prussian blue , nanoparticle , microporous material , coordination polymer , capsule , polymer , anticancer drug , chemistry , nanotechnology , drug , drug carrier , materials science , biomedical engineering , pharmacology , organic chemistry , chemotherapy , medicine , botany , surgery , electrochemistry , biology , electrode

Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC(50) > 1000 μg mL(-1)) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research