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The use of enzymes for construction of DNA-based objects and assemblies
Author(s) -
Sascha Keller,
Andreas Marx
Publication year - 2011
Publication title -
chemical society reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 15.598
H-Index - 513
eISSN - 1460-4744
pISSN - 0306-0012
DOI - 10.1039/c1cs15040e
Subject(s) - dna , nanotechnology , predictability , enzyme , computational biology , chemistry , simplicity , dna origami , computer science , biophysics , biology , biochemistry , materials science , physics , quantum mechanics
DNA has found wide applications in DNA-based nanotechnology due to its simplicity and predictability of its secondary structure. Selecting DNA for the nanoconstruction of objects and assemblies bears the inherent potential for manipulations and control by DNA modifying enzymes. In this tutorial review, we present an overview of the enzyme-catalysed construction of DNA-based objects and assemblies. It is illustrated how a diversity of enzyme-based biochemical reactions are transferred in nanotechnological applications.

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