Asymmetric PPCys: Strongly fluorescing NIR labels | Zendy

Georg Fischer | Zendy; Christian Jüngst | Zendy; Magnus IsomäkiKrondahl | Zendy; Dominik Gauss | Zendy; Heiko M. Möller | Zendy; Ewald Daltrozzo | Zendy; Andreas Zumbusch | Zendy

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Asymmetric PPCys: Strongly fluorescing NIR labels

Author(s) -

Georg Fischer,

Christian Jüngst,

Magnus IsomäkiKrondahl,

Dominik Gauss,

Heiko M. Möller,

Ewald Daltrozzo,

Andreas Zumbusch

Publication year - 2010

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/c0cc00359j

Subject(s) - fluorescence , absorption (acoustics) , internalization , biophysics , narrowband , substitution (logic) , chemistry , fluorescence microscope , nanotechnology , photochemistry , materials science , cell , optics , computer science , biochemistry , biology , physics , composite material , programming language

By a stepwise synthesis strategy biofunctionalized Pyrrolopyrrole Cyanines (PPCy) with an asymmetric substitution pattern were obtained. These exhibit extremely strong and narrowband NIR absorption and fluorescence. Internalization of a peptide bound PPCy is demonstrated using live cell microscopy.

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