Open AccessTotal synthesis of (±)-aspercyclide A and its C19 methyl ether
Author(s) -
James L. Carr,
D.A. Offermann,
M.D. Holdom,
Philip Dusart,
Andrew J. P. White,
Andrew J. Beavil,
Robin J. Leatherbarrow,
Stephen D. Lindell,
Brian J. Sutton,
Alan C. Spivey
Publication year - 2009
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/b923528k
Subject(s) - ether , chemistry , derivative (finance) , stereochemistry , antagonist , medicinal chemistry , organic chemistry , biochemistry , receptor , financial economics , economics
The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.
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