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Engineered nanoparticle surfaces for improved mass spectrometric analyses
Author(s) -
ZhengJiang Zhu,
Vincent M. Rotello,
Richard W. Vachet
Publication year - 2009
Publication title -
the analyst
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 153
eISSN - 1364-5528
pISSN - 0003-2654
DOI - 10.1039/b910428c
Subject(s) - biomolecule , nanoparticle , chemistry , nanotechnology , nucleic acid , mass spectrometry , materials science , chromatography , biochemistry
Engineering of nanoparticle surface functionality provides controlled interactions with biomolecules such as cell membrane lipids, proteins and nucleic acids. Concurrently, this surface chemistry control also opens up new avenues for improving mass spectral analyses. In this Minireview, we highlight some of the emerging work that integrates surface-engineered nanoparticles with mass spectrometry to improve the analysis of a wide variety of chemical and biological systems.

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