Open AccessMeasurement of elastic properties of prostate cancer cells using AFM
Author(s) -
Elsa Correia Faria,
Nan Ma,
Ehsan Gazi,
P. Gardner,
M.D. Brown,
Noel W. Clarke,
Richard D. Snook
Publication year - 2008
Publication title -
the analyst
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 153
eISSN - 1364-5528
pISSN - 0003-2654
DOI - 10.1039/b803355b
Subject(s) - prostate cancer , atomic force microscopy , lncap , hertz , moduli , chemistry , materials science , cancer , nanotechnology , medicine , physics , quantum mechanics
This communication reports that three prostate cancer cells of differing metastatic potential were discriminated based on their Young's moduli (LNCaP - 287 +/- 52 N m(-2), PC-3 - 1401 +/- 162 N m(-2) and BPH - 2797 +/- 491 N m(-2)) which were determined using AFM and the Hertz model.
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