Open AccessNucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases
Author(s) -
Claudia WanningerWeiß,
Francesca Di Pasquale,
Thomas Ehrenschwender,
Andreas Marx,
HansAchim Wagenknecht
Publication year - 2008
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/b718002k
Subject(s) - oligonucleotide , primer (cosmetics) , chemistry , thymine , dna polymerase , dna , nucleotide , primer extension , pyrene , polymerase , uridine , stereochemistry , biochemistry , base sequence , gene , rna , organic chemistry
The chromophores pyrene and bordipyrromethenylbenzene directly linked to the 5-position of uridine are tolerated and recognized as thymine derivatives by DNA polymerases in primer extension experiments.
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