Open AccessSynthesis of urea oligomers and their antibacterial activity
Author(s) -
Haizhong Tang,
Robert J. Doerksen,
Gregory N. Tew
Publication year - 2005
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/b413679a
Subject(s) - bacillus subtilis , urea , antibacterial activity , escherichia coli , amphiphile , chemistry , gram , combinatorial chemistry , polymer chemistry , stereochemistry , organic chemistry , bacteria , biochemistry , copolymer , biology , polymer , genetics , gene
Facially amphiphilic urea oligomers were successfully prepared in a one-pot reaction by carbonyl diimidazole (CDI) coupling and showed greater antibacterial activity against both Gram-negative Escherichia coli and Gram-positive Bacillus subtilis than MSI-78.
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