Open AccessLipolytic and nutritive blood flow response to β-adrenoceptor stimulation in situ in subcutaneous abdominal adipose tissue in obese men
Author(s) -
S.L.H. Schiffelers,
J A P Akkermans,
W.H.M. Saris,
Ellen E. Blaak
Publication year - 2003
Publication title -
international journal of obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.663
H-Index - 225
eISSN - 1476-5497
pISSN - 0307-0565
DOI - 10.1038/sj.ijo.802230
Subject(s) - medicine , endocrinology , adipose tissue , lipolysis , microdialysis , adipocyte , stimulation , isoprenaline , adrenergic , subcutaneous tissue , beta 3 adrenergic receptor , adrenergic receptor , receptor , surgery , central nervous system
beta-Adrenoceptor-mediated whole-body lipolysis is impaired in obesity. This study investigated whether local adipocyte beta-adrenergic sensitivity and changes in nutritive blood flow in subcutaneous abdominal adipose tissue contribute to this impaired response.