
Fasting leptin and appetite responses induced by a 4-day 65%-energy-restricted diet
Author(s) -
Monica Mars,
C. de Graaf,
Lisette C. P. G. M. de Groot,
Caroline van Rossum,
F.J. Kok
Publication year - 2005
Publication title -
international journal of obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.663
H-Index - 225
eISSN - 1476-5497
pISSN - 0307-0565
DOI - 10.1038/sj.ijo.0803070
Subject(s) - appetite , leptin , medicine , endocrinology , caloric theory , intermittent fasting , obesity
Animal studies show that the leptin decline after acute severe caloric restriction is a peripheral signal to increase food intake. However, most human studies have failed to observe such a relationship. We studied the acute effects of severe caloric restriction on the association between serum leptin concentrations and subjective appetite.