Dynamics of proteins and DNA in a Paul trap | Zendy

Kushal Shah | Zendy

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Dynamics of proteins and DNA in a Paul trap

Author(s) -

Kushal Shah

Publication year - 2011

Publication title -

nature precedings

Language(s) - English

Resource type - Journals

ISSN - 1756-0357

DOI - 10.1038/npre.2011.6297.1

Subject(s) - macromolecule , trap (plumbing) , chain (unit) , diffusion , displacement (psychology) , dna , rod , mean squared displacement , dynamics (music) , physics , biophysics , molecular dynamics , chemistry , statistical physics , chemical physics , biology , thermodynamics , computational chemistry , biochemistry , quantum mechanics , medicine , psychology , alternative medicine , pathology , meteorology , psychotherapist , acoustics

Paul traps are increasingly being used in a wide variety of applications in biology including study of protein dynamics and DNA sequencing. In this paper, statistical properties of a macromolecule chain in a Paul trap are theoretically analyzed using a simple model of charged particles connected by rigid rods. It is found that the mean displacement of chain varies linearly with the chain length, showing properties of enhanced diffusion, compared to the normal diffusion relation which exists for the case of a macromolecule chain in a force-free region. The dependence of the mean displacement on the chain length and trap parameters is also found to be very different for the case of pure dc operation and pure ac operation of the Paul trap

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