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On the social induction of Alzheimer's disease: An index theorem aging model for amyloid formation
Author(s) -
Rodrick Wallace,
Deborah Wallace
Publication year - 2011
Publication title -
nature precedings
Language(s) - English
Resource type - Journals
ISSN - 1756-0357
DOI - 10.1038/npre.2011.6012.1
Subject(s) - construct (python library) , disease , folding (dsp implementation) , amyloid (mycology) , index (typography) , neuroscience , protein folding , psychology , medicine , computer science , biology , pathology , microbiology and biotechnology , world wide web , electrical engineering , programming language , engineering
The central 'risk factor' for Alzheimer's disease (AD) is age. From first principles, we construct a mathematical model of protein folding and its in vivo regulation that gives this result in a natural manner. We extend the basic approach using topological information theory methods, and examine a case history of socially-induced premature aging in the United States.

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