Open Accessγδ T cells get adaptive
Author(s) -
Bruno SilvaSantos,
Jessica Strid
Publication year - 2017
Publication title -
nature immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.074
H-Index - 388
eISSN - 1529-2916
pISSN - 1529-2908
DOI - 10.1038/ni.3705
Subject(s) - repertoire , ontogeny , cytomegalovirus , t cell receptor , biology , immunology , microbiology and biotechnology , t cell , virology , evolutionary biology , virus , immune system , genetics , herpesviridae , viral disease , physics , acoustics
Throughout ontogeny, the γδ TCR repertoire in human blood becomes less diverse and more focused, yet is private in nature, and specific adult γδ T cell subsets undergo substantial clonal expansion after challenge with cytomegalovirus
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