Open AccessAurora A in cell division: kinase activity not required
Author(s) -
Elsa Kress,
Monica Gotta
Publication year - 2011
Publication title -
nature cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 11.38
H-Index - 369
eISSN - 1476-4679
pISSN - 1465-7392
DOI - 10.1038/ncb2276
Subject(s) - microbiology and biotechnology , regulator , aurora a kinase , cell division , aurora b kinase , kinase , chromatin , aurora inhibitor , aurora kinase , division (mathematics) , biology , cell , cell cycle , biochemistry , spindle apparatus , dna , gene , arithmetic , mathematics
Aurora A kinase is a key regulator of cell division, whose functions were attributed to its ability to phosphorylate diverse substrates. Aurora A is now shown to have a kinase-independent role in the regulation of chromatin-mediated microtubule assembly.
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