Pancreatic endocrine tumors | Zendy

L. Sylvia | Zendy

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Pancreatic endocrine tumors

Author(s) -

L. Sylvia

Publication year - 2011

Publication title -

modern pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 153

eISSN - 1530-0285

pISSN - 0893-3952

DOI - 10.1038/modpathol.2010.127

Subject(s) - histogenesis , pathology , pancreas , endocrine system , immunohistochemistry , gastrointestinal tract , molecular pathology , biology , medicine , endocrinology , biochemistry , hormone , gene

The endocrine cells of the pancreas and their related cells throughout the gastrointestinal tract give rise to a variety of tumors that pose a diagnostic challenge. There has been progress in understanding their histogenesis, morphology, immunohistochemistry, molecular biology and classifications. This review will focus on nomenclature/terminology, classification, the role of immunohistochemistry, molecular advances, including genetic predisposition, and potential therapeutic targets to define the role of pathology in the application of prognostic and predictive markers for this disease.

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