Dynamics of Regional Distribution of Ischemic Lesions in Middle Cerebral Artery Trunk Occlusion Relates to Collateral Circulation | Zendy

Bastian Cheng | Zendy; Amir Golsari | Zendy; Jens Fiehler | Zendy; Michael Rosenkranz | Zendy; Christian Gerloff | Zendy; Götz Thomalla | Zendy

Open Access

Dynamics of Regional Distribution of Ischemic Lesions in Middle Cerebral Artery Trunk Occlusion Relates to Collateral Circulation

Author(s) -

Bastian Cheng,

Amir Golsari,

Jens Fiehler,

Michael Rosenkranz,

Christian Gerloff,

Götz Thomalla

Publication year - 2010

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.2010.185

Subject(s) - collateral circulation , middle cerebral artery , medicine , trunk , infarction , occlusion , cardiology , stroke (engine) , magnetic resonance imaging , lesion , ischemia , radiology , surgery , myocardial infarction , physics , ecology , biology , thermodynamics

We describe the regional distribution of acute perfusion, diffusion, and final infarct lesions in middle cerebral artery (MCA) trunk occlusion. A total of 31 patients with acute ischemic stroke and MCA trunk occlusion were studied by multiparametric magnetic resonance imaging. Probabilistic maps of lesion distribution were generated. The probability of initial and final infarcts was highest in the central MCA region with decreasing probability toward the periphery where the probability of the tissue at risk of infarction to be saved was highest. The probability of brain regions being involved in acute diffusion lesions and evolving into or escaping from the final infarct relates to the anatomy of arterial blood supply.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research