Increase in Circulating CD34-Positive Cells in Patients with Angiographic Evidence of Moyamoya-like Vessels | Zendy

Tomoyuki Yoshihara | Zendy; Akihiko Taguchi | Zendy; Tomohiro Matsuyama | Zendy; Yoko Shimizu | Zendy; Akie KikuchiTaura | Zendy; Toshihiro Soma | Zendy; David M. Stern | Zendy; Hiroo Yoshikawa | Zendy; Yukiko Kasahara | Zendy; Hiroshi Moriwaki | Zendy; Kazuyuki Nagatsuka | Zendy; Hiroaki Naritomi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Increase in Circulating CD34-Positive Cells in Patients with Angiographic Evidence of Moyamoya-like Vessels

Author(s) -

Tomoyuki Yoshihara,

Akihiko Taguchi,

Tomohiro Matsuyama,

Yoko Shimizu,

Akie KikuchiTaura,

Toshihiro Soma,

David M. Stern,

Hiroo Yoshikawa,

Yukiko Kasahara,

Hiroshi Moriwaki,

Kazuyuki Nagatsuka,

Hiroaki Naritomi

Publication year - 2008

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.2008.1

Subject(s) - cd34 , medicine , neovascularization , progenitor cell , stenosis , occlusion , cardiology , angiogenesis , stem cell , biology , genetics

Increasing evidence points to a role for circulating endothelial progenitor cells, including populations of CD34-positive (CD34 + ) cells, in maintenance of cerebral blood flow. In this study, we investigated the link between the level of circulating CD34 + cells and neovascularization at ischemic brain. Compared with control subjects, a remarkable increase of circulating CD34 + cells was observed in patients with angiographic moyamoya vessels, although no significant change was observed in patients with major cerebral artery occlusion (or severe stenosis) but without moyamoya vessels. Our results suggest that the increased level of CD34 + cells associated with ischemic stress is correlated with neovascularization at human ischemic brain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research