Specification and Selection of Regions of Interest (ROIs) in a Computerized Brain Atlas | Zendy

C. Bohm | Zendy; T. Greitz | Zendy; R Seitz | Zendy; Lars Eriksson | Zendy

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Specification and Selection of Regions of Interest (ROIs) in a Computerized Brain Atlas

Author(s) -

C. Bohm,

T. Greitz,

R Seitz,

Lars Eriksson

Publication year - 1991

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.1991.39

Subject(s) - atlas (anatomy) , positron emission tomography , neuroimaging , brain atlas , magnetic resonance imaging , computer science , tomography , brain mapping , artificial intelligence , nuclear medicine , medicine , neuroscience , radiology , psychology , anatomy

The computerized individually adjustable brain atlas (CBA) has been further developed. The atlas was primarily designed for anatomical localization and quantitative evaluation of data in positron emission tomography (PET), but may also be employed for other neuroimaging modalities, such as transmission computed tomography (CT) and magnetic resonance imaging (MRI). The atlas is based on anatomical information obtained from digitized cryosectioned brains. Using spatially standardized and then averaged MRI images, we demonstrate the high localization accuracy and precision of the brain atlas. This is a prerequisite for obtaining accuracy when using the atlas in the localization and the quantitative evaluation of PET data. The specification and the selection of region of interests (ROIs) by the CBA are presented and discussed.

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