Brain Blood Volume, Flow, and Oxygen Utilization Measured with 15O Radiotracers and Positron Emission Tomography: Revised Metabolic Computations | Zendy

Tom O. Videen | Zendy; Joel S. Perlmutter | Zendy; Peter Herscovitch | Zendy; Marcus E. Raichle | Zendy

Open Access

Brain Blood Volume, Flow, and Oxygen Utilization Measured with ¹⁵O Radiotracers and Positron Emission Tomography: Revised Metabolic Computations

Author(s) -

Tom O. Videen,

Joel S. Perlmutter,

Peter Herscovitch,

Marcus E. Raichle

Publication year - 1987

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.1987.97

Subject(s) - positron emission tomography , positron , blood flow , nuclear medicine , cerebral blood flow , positron emission , volume (thermodynamics) , physics , tomography , oxygen , computation , brain positron emission tomography , radiochemistry , chemistry , nuclear physics , medicine , mathematics , preclinical imaging , algorithm , radiology , thermodynamics , optics , in vivo , quantum mechanics , electron , microbiology and biotechnology , biology

We have revised our methods for calculating regional blood volume, flow, oxygen extraction, and oxygen utilization from positron emission tomography data obtained using 15O-labeled radiotracers. These revisions include radioactive decay explicitly within the model equations instead of requiring all measured activity to be corrected for decay prior to incorporation in the equations. The revised equations yield small but significant differences in the computed values.

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