On the Construction of Functional Maps in Positron Emission Tomography | Zendy

G. Blomqvist | Zendy

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On the Construction of Functional Maps in Positron Emission Tomography

Author(s) -

G. Blomqvist

Publication year - 1984

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.1984.89

Subject(s) - positron emission tomography , deoxyglucose , positron , tracer , nuclear medicine , nonlinear system , positron emission , physics , tomography , cerebral blood flow , algorithm , biological system , computer science , biomedical engineering , chemistry , optics , nuclear physics , medicine , biochemistry , quantum mechanics , electron , biology , cardiology

A linear algorithm for the rapid calculation of local rate constants is proposed. The method is applicable to the three-compartment models currently used in the analysis of positron camera measurements with [ 11 C]methionine, [ 11 C]deoxyglucose, and [ 11 C]glucose. The same technique can also be used for the regional measurement of local blood flow with the aid of a freely diffusible tracer. The algorithm was applied to measurements on humans with [ 11 C]glucose. As a comparison, the same data were also analyzed with a standard nonlinear technqiue. Good agreement between the two methods was obtained.

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