Immunoreactive Glucagon in the Smooth Muscle Cells of the Rat Cerebral Artery: An Immunohistochemical Analysis
Author(s) -
Tomohiro Matsuyama,
Tomohiro Sadao,
Masayasu Matsumoto,
Masayuki Mieno,
Shotaro Yoneda,
Kazufumi Kimura,
Norio Hayashi,
Takenobu Kamada,
Hiroshi Abe,
Tōru Hayakawa,
Hirohito Tsubouchi,
Masaya Tohyama
Publication year - 1984
Publication title -
journal of cerebral blood flow and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.167
H-Index - 193
eISSN - 1559-7016
pISSN - 0271-678X
DOI - 10.1038/jcbfm.1984.43
Subject(s) - glucagon , radioimmunoassay , immunohistochemistry , antiserum , medicine , endocrinology , cerebral arteries , smooth muscle , middle cerebral artery , chemistry , antibody , insulin , immunology , ischemia
The presence of immunoreactive glucagon (IRG) in smooth muscle of the cerebral arteries of rats was demonstrated immunohistochemically using two antisera against pancreatic glucagon, OAL-123 and Unger's 30K. Based on the results and on our previous radioimmunoassay and gel filtration study, the smooth muscle cells of the blood vessels may be one of the extrapancreatic sources of IRG in the plasma.
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