Measurement of Local Blood Flow and Distribution Volume with Short-Lived Isotopes: A General Input Technique | Zendy

SungCheng Huang | Zendy; Richard E. Carson | Zendy; Michael E. Phelps | Zendy

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Measurement of Local Blood Flow and Distribution Volume with Short-Lived Isotopes: A General Input Technique

Author(s) -

SungCheng Huang,

Richard E. Carson,

Michael E. Phelps

Publication year - 1982

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.1982.11

Subject(s) - volume (thermodynamics) , isotope , basis (linear algebra) , blood flow , flow (mathematics) , distribution (mathematics) , constant (computer programming) , computer science , statistical physics , mechanics , physics , mathematics , mathematical analysis , nuclear physics , thermodynamics , geometry , medicine , programming language

A new technique for measuring local blood flow and distribution volume is proposed. The technique uses short-lived isotopes but is different from the equilibrium method in that no constant input is necessary, and no assumption about distribution volume is needed. The theoretical basis of the technique is developed, and the results of a computer-simulation study are presented to show the potential of the technique. The technique is expected to be easier to perform and to give more accurate flow values than the equilibrium method.

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