Alterations in Local Cerebral Glucose Utilisation in Specific Thalamic Nuclei following Apomorphine | Zendy

James McCulloch | Zendy; Paul A. Kelly | Zendy

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Alterations in Local Cerebral Glucose Utilisation in Specific Thalamic Nuclei following Apomorphine

Author(s) -

James McCulloch,

Paul A. Kelly

Publication year - 1981

Publication title -

journal of cerebral blood flow and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.167

H-Index - 193

eISSN - 1559-7016

pISSN - 0271-678X

DOI - 10.1038/jcbfm.1981.14

Subject(s) - apomorphine , thalamus , geniculate , deoxyglucose , chemistry , neuroscience , medicine , endocrinology , biology , nucleus , dopamine , dopaminergic

The alterations in local cerebral glucose utilisation in eight discrete nuclei in the thalamus following the administration of apomorphine (0.5 mg kg-1) have been investigated with the autoradiographic 2-deoxyglucose technique in 11 conscious rats. In two thalamic nuclei (parafascicular and ventrolateral nuclei), glucose utilisation was significantly elevated following apomorphine; in two thalamic nuclei (the anterior medial and anterior ventral nuclei), glucose utilisation was significantly reduced following apomorphine; and in four nuclei (lateral geniculate, medial geniculate, mediodorsal, and lateral thalamic nuclei), glucose use was unchanged.

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