Association between MC4R rs17782313 polymorphism and overeating behaviors
Author(s) -
Zeynep Yılmaz,
Caroline Davis,
Natalie J. Loxton,
A S Kaplan,
R D Levitan,
J C Carter,
James L. Kennedy
Publication year - 2014
Publication title -
international journal of obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.663
H-Index - 225
eISSN - 1476-5497
pISSN - 0307-0565
DOI - 10.1038/ijo.2014.79
Subject(s) - overeating , body mass index , mood , emotional eating , obesity , medicine , appetite , weight change , melanocortin 4 receptor , weight gain , endocrinology , melanocortin , clinical psychology , weight loss , body weight , eating behavior , receptor
Melanocortins have a crucial role in appetite and weight regulation. Although the melanocortin 4 receptor (MC4R) gene has been repeatedly linked to obesity and antipsychotic-induced weight gain, the mechanism behind how it leads to this effect in still undetermined. The goal of this study was to conduct an in-depth and sophisticated analysis of MC4R polymorphisms, body mass index (BMI), eating behavior and depressed mood.
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