Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA | Zendy

Christina Holzapfel | Zendy; Harald Grallert | Zendy; Cornelia Huth | Zendy; Simone Wahl | Zendy; Britta Fischer | Zendy; Angela Döring | Zendy; InaMaria Rückert | Zendy; Anke Hinney | Zendy; Johannes Hebebrand | Zendy; H-E Wichmann | Zendy; Hans Hauner | Zendy; Thomas Illig | Zendy; Iris M. Heid | Zendy

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Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA

Author(s) -

Christina Holzapfel,

Harald Grallert,

Cornelia Huth,

Simone Wahl,

Britta Fischer,

Angela Döring,

InaMaria Rückert,

Anke Hinney,

Johannes Hebebrand,

H-E Wichmann,

Hans Hauner,

Thomas Illig,

Iris M. Heid

Publication year - 2010

Publication title -

international journal of obesity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.663

H-Index - 225

eISSN - 1476-5497

pISSN - 0307-0565

DOI - 10.1038/ijo.2010.79

Subject(s) - body mass index , obesity , single nucleotide polymorphism , genetic association , demography , fto gene , medicine , snp , genome wide association study , polymorphism (computer science) , population , allele , genetics , genotype , biology , gene , environmental health , sociology

Data from meta-analyses of genome-wide association studies provided evidence for an association of polymorphisms with body mass index (BMI), and gene expression results indicated a role of these variants in the hypothalamus. It was consecutively hypothesized that these associations might be evoked by a modulation of nutritional intake or energy expenditure.

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