MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer | Zendy

Maegan E. Roberts | Zendy; Sarah Jackson | Zendy; Lisa R. Susswein | Zendy; Nur Zeinomar | Zendy; Xinran Ma | Zendy; Megan L. Marshall | Zendy; Amy Stettner | Zendy; Becky Milewski | Zendy; Zhixiong Xu | Zendy; Benjamin D. Solomon | Zendy; Mary Beth Terry | Zendy; Kathleen S. Hruska | Zendy; Rachel T. Klein | Zendy; Wendy K. Chung | Zendy

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MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer

Author(s) -

Maegan E. Roberts,

Sarah Jackson,

Lisa R. Susswein,

Nur Zeinomar,

Xinran Ma,

Megan L. Marshall,

Amy Stettner,

Becky Milewski,

Zhixiong Xu,

Benjamin D. Solomon,

Mary Beth Terry,

Kathleen S. Hruska,

Rachel T. Klein,

Wendy K. Chung

Publication year - 2018

Publication title -

genetics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.509

H-Index - 128

eISSN - 1530-0366

pISSN - 1098-3600

DOI - 10.1038/gim.2017.254

Subject(s) - msh6 , mlh1 , breast cancer , lynch syndrome , medicine , msh2 , oncology , population , pms2 , family history , cancer , gynecology , colorectal cancer , environmental health , dna mismatch repair

An association of Lynch syndrome (LS) with breast cancer has been long suspected; however, there have been insufficient data to address this question for each of the LS genes individually.

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