Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility | Zendy

Angela R. Bradbury | Zendy; Linda PatrickMiller | Zendy; Jessica M. Long | Zendy; Jacquelyn Powers | Zendy; Jill E. Stopfer | Zendy; Andrea Forman | Zendy; Christina Rybak | Zendy; Kristin Mattie | Zendy; Amanda Brandt | Zendy; Rachelle Chambers | Zendy; Wendy K. Chung | Zendy; Jane E. Churpek | Zendy; Mary B. Daly | Zendy; Laura DiGiovanni | Zendy; Dana Farengo-Clark | Zendy; Dominique Fetzer | Zendy; Pamela Ganschow | Zendy; Generosa Grana | Zendy; Cassandra Gulden | Zendy; Michael J. Hall | Zendy; Lynne Kohler | Zendy; Kara N. Maxwell | Zendy; Shana L. Merrill | Zendy; Susan Montgomery | Zendy; Rebecca Mueller | Zendy; Sarah M. Nielsen | Zendy; Olufunmilayo I. Olopade | Zendy; Kimberly Rainey | Zendy; Christina Seelaus | Zendy; Katherine L. Nathanson | Zendy; Susan M. Domchek | Zendy

Open Access

Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility

Author(s) -

Angela R. Bradbury,

Linda PatrickMiller,

Jessica M. Long,

Jacquelyn Powers,

Jill E. Stopfer,

Andrea Forman,

Christina Rybak,

Kristin Mattie,

Amanda Brandt,

Rachelle Chambers,

Wendy K. Chung,

Jane E. Churpek,

Mary B. Daly,

Laura DiGiovanni,

Dana Farengo-Clark,

Dominique Fetzer,

Pamela Ganschow,

Generosa Grana,

Cassandra Gulden,

Michael J. Hall,

Lynne Kohler,

Kara N. Maxwell,

Shana L. Merrill,

Susan Montgomery,

Rebecca Mueller,

Sarah M. Nielsen,

Olufunmilayo I. Olopade,

Kimberly Rainey,

Christina Seelaus,

Katherine L. Nathanson,

Susan M. Domchek

Publication year - 2014

Publication title -

genetics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.509

H-Index - 128

eISSN - 1530-0366

pISSN - 1098-3600

DOI - 10.1038/gim.2014.134

Subject(s) - informed consent , genetic testing , multiplex , genetic counseling , medicine , penetrance , multidisciplinary approach , family medicine , medical physics , psychology , bioinformatics , genetics , alternative medicine , pathology , biology , gene , social science , sociology , phenotype

Multiplex genetic testing, including both moderate- and high-penetrance genes for cancer susceptibility, is associated with greater uncertainty than traditional testing, presenting challenges to informed consent and genetic counseling. We sought to develop a new model for informed consent and genetic counseling for four ongoing studies.

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