Open AccessAge-specific Parkinson disease risk in GBA mutation carriers: information for genetic counseling
Author(s) -
Huma Q. Rana,
Manisha Balwani,
Louise Bier,
Roy N. Alcalay
Publication year - 2012
Publication title -
genetics in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.509
H-Index - 128
eISSN - 1530-0366
pISSN - 1098-3600
DOI - 10.1038/gim.2012.107
Subject(s) - disease , penetrance , medicine , glucocerebrosidase , family history , genetic counseling , parkinson's disease , genetic testing , age of onset , pediatrics , genetics , biology , gene , phenotype
We sought to estimate age-specific risk of Parkinson disease in relatives of patients with Gaucher disease, who are obligate carriers of GBA mutations and who were not ascertained by family history of Parkinson disease.
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