Genetic Characterization and Influence on Inflammatory Bowel Disease Expression in a Diverse Hispanic South Florida Cohort
Author(s) -
Oriana M. Damas,
Lissette Gomez,
Maria A. Quintero,
Evadnie Rampersaud,
Susan Slifer,
Gary W. Beecham,
David H. Kerman,
Amar R. Deshpande,
Daniel A. Sussman,
María T. Abreu,
Jacob L. McCauley
Publication year - 2017
Publication title -
clinical and translational gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.673
H-Index - 35
ISSN - 2155-384X
DOI - 10.1038/ctg.2017.13
Subject(s) - medicine , inflammatory bowel disease , ulcerative colitis , genetic testing , genetic predisposition , cohort , allele , disease , population , crohn's disease , genetics , gene , biology , environmental health
This study highlights the fundamental importance of these loci in IBD pathogenesis including in our diverse Hispanic population. Future studies looking at non-genetic mechanisms of disease are needed to explain differences in age of presentation and phenotype between Hispanics and NHW.
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