The Role of Gut–brain Axis in Regulating Glucose Metabolism After Acute Pancreatitis | Zendy

Sayali A. Pendharkar | Zendy; Varsha Asrani | Zendy; Rinki Murphy | Zendy; Richard Cutfield | Zendy; John A. Windsor | Zendy; Maxim S. Petrov | Zendy

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The Role of Gut–brain Axis in Regulating Glucose Metabolism After Acute Pancreatitis

Author(s) -

Sayali A. Pendharkar,

Varsha Asrani,

Rinki Murphy,

Richard Cutfield,

John A. Windsor,

Maxim S. Petrov

Publication year - 2017

Publication title -

clinical and translational gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.673

H-Index - 35

ISSN - 2155-384X

DOI - 10.1038/ctg.2016.63

Subject(s) - medicine , pancreatitis , acute pancreatitis , gut–brain axis , carbohydrate metabolism , metabolism , bioinformatics , neuroscience , intensive care medicine , biology , disease

Fasting circulating oxyntomodulin, glicentin, and VIP levels are significantly decreased in patients with defective glucose homeostasis after acute pancreatitis. Oxyntomodulin appears to be a promising therapeutic target for future clinical studies on diabetes associated with diseases of the exocrine pancreas.

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