Metabolic Profiling of the Impact of Oligofructose-Enriched Inulin in Crohn's Disease Patients: A Double-Blinded Randomized Controlled Trial | Zendy

Vicky De Preter | Zendy; Marie Joossens | Zendy; Vera Ballet | Zendy; Ziv Shkedy | Zendy; Paul Rutgeerts | Zendy; Séverine Vermeire | Zendy; Kristin Verbeke | Zendy

Open Access

Metabolic Profiling of the Impact of Oligofructose-Enriched Inulin in Crohn's Disease Patients: A Double-Blinded Randomized Controlled Trial

Author(s) -

Vicky De Preter,

Marie Joossens,

Vera Ballet,

Ziv Shkedy,

Paul Rutgeerts,

Séverine Vermeire,

Kristin Verbeke

Publication year - 2013

Publication title -

clinical and translational gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.673

H-Index - 35

ISSN - 2155-384X

DOI - 10.1038/ctg.2012.24

Subject(s) - metabolite , medicine , placebo , feces , gastroenterology , prebiotic , crohn's disease , randomized controlled trial , butyrate , inulin , dysbiosis , food science , disease , chemistry , biology , fermentation , microbiology and biotechnology , pathology , alternative medicine

Although intestinal dysbiosis is well established in Crohn's disease (CD), little is known about the microbial metabolic activity of CD patients. In this study, we compared the metabolite patterns of the CD patients with profiles from healthy controls (HCs) and correlated them to disease activity and bacterial composition. In addition, the influence of the prebiotic oligofructose-enriched inulin (OF-IN) on the CD metabolites profile was evaluated.status: publishe

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