Open AccessCeliac disease: a model disease for gene–environment interaction
Author(s) -
Raivo Uibo,
Zhigang Tian,
M. Eric Gershwin
Publication year - 2011
Publication title -
cellular and molecular immunology/cellular and molecular immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.5
H-Index - 81
eISSN - 2042-0226
pISSN - 1672-7681
DOI - 10.1038/cmi.2010.62
Subject(s) - disease , autoimmunity , theme (computing) , key (lock) , biology , medicine , computer science , ecology , pathology , operating system
Celiac sprue remains a model autoimmune disease for dissection of genetic and environmental influences on disease progression. The 2010 Congress of Autoimmunity included several key sessions devoted to genetics and environment. Several papers from these symposia were selected for in-depth discussion and publication. This issue is devoted to this theme. The goal is not to discuss genetic and environmental interactions, but rather to focus on key elements of diagnosis, the inflammatory response and the mechanisms of autoimmunity.