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An unusual case of B-ALL occurring in a patient with acute promyelocytic leukemia in remission after two hematopoietic SCTs: whose are the leukemic cells?
Author(s) -
Sara Bigliardi,
Monica Morselli,
Leonardo Potenza,
Paola Bresciani,
Aurora Cuoghi,
Valeria Coluccio,
Giovanni Riva,
Ambra Paolini,
Valeria Fantuzzi,
Laura Faglioni,
Vincenzo Nasillo,
Andrea Messerotti,
Roberto Marasca,
Franco Narni,
Mario Luppi,
Fabio Forghieri
Publication year - 2014
Publication title -
bone marrow transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 127
eISSN - 1476-5365
pISSN - 0268-3369
DOI - 10.1038/bmt.2014.119
Subject(s) - medicine , acute promyelocytic leukemia , haematopoiesis , leukemia , oncology , stem cell , retinoic acid , genetics , cell culture , biology
We read with interest the recent article by Shiozaki H, et al. (Bone Marrow Transplant 2014; 49: 102–109) reporting a case of donor cell leukemia (DCL) occurring in a patient who previously underwent cord blood (CB) transplantation for myelodysplastic syndrome and describing the clinical and biological differences between DCL arising after hematopoietic SCT (HSCT) from either CB or BM sources. We would like to comment on these issues, reporting an unusual case of DCL in a patient with a long history of acute promyelocytic leukemia (APL)

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