KRAS mutations detected by the amplification refractory mutation system–Scorpion assays strongly correlate with therapeutic effect of cetuximab
Author(s) -
Hideaki Bando,
Takayuki Yoshino,
Katsuya Tsuchihara,
Naomi Ogasawara,
Nozomu Fuse,
Takashi Kojima,
Makoto Tahara,
Motohiro Kojima,
Kensuke Kaneko,
Toshihiko Doi,
Atsushi Ochiai,
Hiroyasu Esumi,
Atsushi Ohtsu
Publication year - 2011
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/bjc.2011.247
Subject(s) - kras , cetuximab , medicine , refractory (planetary science) , oncology , gastroenterology , biology , colorectal cancer , cancer , astrobiology
We aimed to compare the sensitive and quality-controlled KRAS testing with direct sequencing and to assess the impact on decision making of treatment.
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