Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome | Zendy

Bo Wängberg | Zendy; H. Ahlman | Zendy; U. Tylén | Zendy; Ola Nilsson | Zendy; Svante Hermodsson | Zendy; Kristoffer Hellstrand | Zendy

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Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome

Author(s) -

Bo Wängberg,

H. Ahlman,

U. Tylén,

Ola Nilsson,

Svante Hermodsson,

Kristoffer Hellstrand

Publication year - 1995

Publication title -

british journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.833

H-Index - 236

eISSN - 1532-1827

pISSN - 0007-0920

DOI - 10.1038/bjc.1995.120

Subject(s) - lymphocytosis , midgut , medicine , pathology , carcinoid syndrome , biology , botany , larva

Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

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