High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer | Zendy

Hans Jørgen Nielsen | Zendy; Gedske Daugaard | Zendy; Michael Tvede | Zendy; Brita Bruun | Zendy

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High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer

Author(s) -

Hans Jørgen Nielsen,

Gedske Daugaard,

Michael Tvede,

Brita Bruun

Publication year - 1992

Publication title -

british journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.833

H-Index - 236

eISSN - 1532-1827

pISSN - 0007-0920

DOI - 10.1038/bjc.1992.334

Subject(s) - clostridium difficile , medicine , chemotherapy , etiology , clostridiaceae , diarrhea , germ cell tumors , cancer , antibiotics , pathogen , immunology , microbiology and biotechnology , biology , toxin

A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients.

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