Treatments affecting the rate of asbestos-induced mesotheliomas | Zendy

J. C. Wagner | Zendy; Ronald J. Hill | Zendy; Geoffrey Berry | Zendy; M M Wagner | Zendy

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Treatments affecting the rate of asbestos-induced mesotheliomas

Author(s) -

J. C. Wagner,

Ronald J. Hill,

Geoffrey Berry,

M M Wagner

Publication year - 1980

Publication title -

british journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.833

H-Index - 236

eISSN - 1532-1827

pISSN - 0007-0920

DOI - 10.1038/bjc.1980.169

Subject(s) - mesothelioma , asbestos , talc , medicine , saline , chrysotile , carrageenan , pleural disease , pleural cavity , pathology , lung , respiratory disease , surgery , biology , pharmacology , paleontology , materials science , metallurgy

256 Wistar rats received a single injection into the right pleural cavity of UICC crocidolite in order to induce mesotheliomas. They were then given right intrapleural injectons of BCG, crystalline silica, talc, carrageenan or saline (as a control). There was no significant change in the mesothelioma rate in the rats exposed to BCG, silica or talc, but there was a 3-fold increase in mesothelioma incidence in the group injected with carrageenan.

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