Vascular and Cardiac Effects of Grape Powder in the Spontaneously Hypertensive Rat
Author(s) -
Sijo Joseph Thandapilly,
Jillian L. LeMaistre,
Xavier Lieben Louis,
Christopher M. Anderson,
Thomas Netticadan,
H. D. Anderson
Publication year - 2012
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2012.98
Subject(s) - medicine , blood pressure , cardiology , left ventricular hypertrophy , cardiac function curve , spontaneously hypertensive rat , muscle hypertrophy , mesenteric arteries , arterial stiffness , electrical impedance myography , artery , endocrinology , vasodilation , heart failure
We previously reported that resveratrol, a polyphenol found in red grapes, attenuated changes in small artery geometry and stiffness, as well as cardiac hypertrophy and cardiac function in the spontaneously hypertensive rat (SHR). However, in addition to resveratrol, grapes contain a variety of bioactive polyphenols such as catechins, anthocyanins, and flavonoids. Therefore, we investigated the effects of grape consumption in SHR.
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