Nitric Oxide Synthase-Dependent Vasodilation of Human Subcutaneous Arterioles Correlates With Noninvasive Measurements of Endothelial Function | Zendy

Kodlipet Dharmashankar | Zendy; Aimee Welsh | Zendy; Jingli Wang | Zendy; Tinoy Kizhakekuttu | Zendy; Rong Ying | Zendy; David D. Gutterman | Zendy; Michael E. Widlansky | Zendy

Open Access

Nitric Oxide Synthase-Dependent Vasodilation of Human Subcutaneous Arterioles Correlates With Noninvasive Measurements of Endothelial Function

Author(s) -

Kodlipet Dharmashankar,

Aimee Welsh,

Jingli Wang,

Tinoy Kizhakekuttu,

Rong Ying,

David D. Gutterman,

Michael E. Widlansky

Publication year - 2012

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2012.8

Subject(s) - medicine , vasodilation , arteriole , nitric oxide synthase , endothelial nitric oxide synthase , cardiology , nitric oxide , microcirculation , enos

Noninvasive measurements of endothelial function predict future adverse cardiovascular events, but offer limited opportunities for mechanistic insights into phenotypic observations. Subcutaneous adipose arterioles, accessible through minimally invasive methods, provide an opportunity for complimentary mechanistic studies. Limited data relating subcutaneous arteriolar endothelial function, cardiovascular risk factors, and noninvasive measurements of endothelial function currently exist.

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