Left Ventricular Structure and Function in Relation to Steroid Biosynthesis Genes in a White Population | Zendy

Yu Jin | Zendy; Tatiana Kuznetsova | Zendy; Lorena Citterio | Zendy; Lutgarde Thijs | Zendy; Elisabetta Messaggio | Zendy; Nunzia Casamassima | Zendy; Paolo Manunta | Zendy; Robert Fagard | Zendy; Giuseppe Bianchi | Zendy; Jan A. Staessen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Left Ventricular Structure and Function in Relation to Steroid Biosynthesis Genes in a White Population

Author(s) -

Yu Jin,

Tatiana Kuznetsova,

Lorena Citterio,

Lutgarde Thijs,

Elisabetta Messaggio,

Nunzia Casamassima,

Paolo Manunta,

Robert Fagard,

Giuseppe Bianchi,

Jan A. Staessen

Publication year - 2012

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2012.69

Subject(s) - medicine , endocrinology , aldosterone , single nucleotide polymorphism , haplotype , population , diastole , genotype , cardiology , biology , blood pressure , genetics , gene , environmental health

Both endogenous ouabain (EO) and aldosterone are steroid hormones which might play a role in the pathogenesis of left ventricular (LV) hypertrophy and cardiac remodeling. Cholesterol side-chain cleavage enzyme (CYP11A1) and 3β-hydroxysteroid dehydrogenase (HSD3B1) are two key enzymes in the pathway of steroid biosynthesis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research