Arterial Stiffness Is Associated With Increased Monocyte Expression of Adiponectin Receptor mRNA and Protein in Patients With Coronary Artery Disease
Author(s) -
Ignatios Ikonomidis,
Nikolaos P.E. Kadoglou,
Panayoula C. Tsiotra,
Αναστάσιος Κόλλιας,
Ifaistion M. Palios,
Katerina Fountoulaki,
Panagiotis Halvatsiotis,
Eirini Maratou,
George Dimitriadis,
Dimitrios Kremastinos,
J. Lekakis,
S. Raptis
Publication year - 2012
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2012.42
Subject(s) - medicine , pulse wave velocity , adiponectin , adiponectin receptor 1 , arterial stiffness , coronary artery disease , cardiology , endocrinology , osteoprotegerin , receptor , messenger rna , artery , blood pressure , biology , gene , insulin resistance , biochemistry , activator (genetics) , insulin
Arterial stiffness and carotid intima-media thickness (IMT) constitute validated cardiovascular prognostic markers. Adiponectin and its receptors 1 (AdipoR1) and 2 (AdipoR2) are involved in coronary artery disease (CAD). We investigated whether AdipoR1 and R2 mRNA and protein expression are associated with arterial stiffness, IMT and extent of coronary atherosclerosis.
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