Aldosterone-to-Renin Ratio as a Predictor of Stroke Under Conditions of High Sodium Intake: The Ohasama Study | Zendy

Michihiro Satoh | Zendy; Masahiro Kikuya | Zendy; Takayoshi Ohkubo | Zendy; Trevor A. Mori | Zendy; Hirohito Metoki | Zendy; Azusa Hara | Zendy; Megumi Utsugi | Zendy; Teruo Hashimoto | Zendy; Takuo Hirose | Zendy; Taku Obara | Zendy; Ryusuke Inoue | Zendy; K Asayama | Zendy; A. Kanno | Zendy; Kazuhito Totsune | Zendy; H. Hoshi | Zendy; H. Satoh | Zendy; Yohsuke Imai | Zendy

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Aldosterone-to-Renin Ratio as a Predictor of Stroke Under Conditions of High Sodium Intake: The Ohasama Study

Author(s) -

Michihiro Satoh,

Masahiro Kikuya,

Takayoshi Ohkubo,

Trevor A. Mori,

Hirohito Metoki,

Azusa Hara,

Megumi Utsugi,

Teruo Hashimoto,

Takuo Hirose,

Taku Obara,

Ryusuke Inoue,

K Asayama,

A. Kanno,

Kazuhito Totsune,

H. Hoshi,

H. Satoh,

Yohsuke Imai

Publication year - 2012

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1038/ajh.2012.33

Subject(s) - medicine , aldosterone , hazard ratio , blood pressure , body mass index , endocrinology , plasma renin activity , stroke (engine) , proportional hazards model , renin–angiotensin system , population , sodium , prospective cohort study , confidence interval , chemistry , mechanical engineering , environmental health , organic chemistry , engineering

Aldosterone is thought to have deleterious effects on the cardiovascular system. The aldosterone-to-renin ratio (ARR) is more reproducible than aldosterone levels alone and could be an index for inappropriate aldosterone secretion or activity. We previously reported the apparent relation between ARR and hypertension in subjects with high sodium intake. This prospective study investigated the risk of ARR for a first stroke in a general population stratified by sodium intake.

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