Amlodipine enhances amelioration of vascular insulin resistance, oxidative stress, and metabolic disorders by candesartan in metabolic syndrome rats
Author(s) -
Daisuke Sueta,
Taishi Nakamura,
YiFei Dong,
Keiichiro Kataoka,
Nobutaka Koibuchi,
Eiichiro Yamamoto,
Kensuke Toyama,
Osamu Yasuda,
Hisao Ogawa,
Shokei KimMitsuyama
Publication year - 2012
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2012.26
Subject(s) - candesartan , medicine , metabolic syndrome , insulin resistance , oxidative stress , amlodipine , endocrinology , diabetes mellitus , insulin , blood pressure , angiotensin ii
The pharmacological advantage of combination of an angiotensin receptor blocker (ARB) and a calcium-channel blocker (CCB) is not fully defined. This study was undertaken to elucidate the potential benefit of their combination in metabolic syndrome.
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