Open AccessSNPs in MicroRNA Binding Sites in 3′-UTRs of RAAS Genes Influence Arterial Blood Pressure and Risk of Myocardial Infarction
Author(s) -
A. Yaël Nossent,
Jakob L. Hansen,
Carine J.M. Doggen,
Paul H.A. Quax,
Søren P. Sheikh,
Frits R. Rosendaal
Publication year - 2011
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1038/ajh.2011.92
Subject(s) - single nucleotide polymorphism , blood pressure , snp , medicine , myocardial infarction , allele , endocrinology , genetics , biology , gene , genotype
We hypothesized that single nucleotide polymorphisms (SNPs) located in microRNA (miR) binding sites in genes of the renin angiotensin aldosterone system (RAAS) can influence blood pressure and risk of myocardial infarction.
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